Volume 8: Variant CJD
Index

A

abnormal reflexes

ACDP

Acheson, Sir Donald  2,  3

Advisory Committee on Dangerous Pathogens see ACDP

age distribution  2

age factors

Agricultural Research Council see ARC

Agriculture Select Committee  2

akinetic mutism  2

Allen, Professor Ingrid  2,  3,  4

Alzheimer's disease

ARC  2

Association of British Neurologists

ataxia  2,  3

autopsy material

B

BBSRC

beef farmers

beef, safety  2,  3

Bell, Dr Jeanne  2

biopsies

Biotechnology and Biological Sciences Research Council see BBSRC

Births and Deaths Registration Act 1953  2

black pudding

blood tests  2

bovine origin medicinal products

Bovine Spongiform Encephalopathy see BSE

BPSU see British Paediatric Surveillance Unit

brain (cattle)  2,  3

brain biopsy  2,  3,  4,  5

brain imaging

British Neurological Surveillance Unit

British Paediatric Association

British Paediatric Surveillance Unit  2

BSE  2,  3,  4

BSE agent

BSE and CJD  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12,  13

BSE, and vCJD  2,  3,  4,  5,  6

BSE, transmission to humans  2,  3

BSE-affected cattle  2,  3,  4,  5,  6

Burgess, Michael  2,  3

butchers

C

Calman, Sir Kenneth (CMO)  2,  3

calving  2

case-control analysis

catteries

cattle brain  2,  3

cattle farmers

cattle feed

cattle feed dust

cause of death, identification

CDSC  2,  3,  4

central nervous system

Central Veterinary Laboratory see CVL

Centre for Applied Microbiology and Research, Porton Down

Centre for Genome Research, Edinburgh  2

cerebellar syndrome  2,  3

cerebrospinal fluid

Chief Medical Officer see CMO

CJD  2

CJD and BSE  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12,  13

CJD Neuropathology Surveillance project

CJD patients

CJD see also familial CJD, hGH-derived CJD, iatrogenic CJD, sporadic CJD

CJD studies  2

CJD Support Network  2

CJD Surveillance Unit see CJDSU

CJD surveillance, recommendations  2

CJD, biochemical detection

CJD, cases  2,  3,  4

CJD, clinical characteristics

CJD, clinical features  2

CJD, deaths

CJD, diagnosis methods

CJD, diagnostic criteria

CJD, diagnostic test

CJD, epidemiology  2,  3,  4,  5,  6

CJD, geographical distribution  2

CJD, identification

CJD, incidence  2,  3,  4,  5,  6

CJD, incidence studies  2

CJD, links to diet  2

CJD, neuropathology  2

CJD, notifiable disease

CJD, person-to-person transmission

CJD, prospective surveillance

CJD, surveillance, European  2

CJD, susceptibility

CJD, transmission

CJDSU  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12,  13,  14,  15,  16,  17,  18,  19

CJDSU, Fifth Annual Report 1996

CJDSU, Fourth Annual Report

CJDSU, funding

CJDSU, prospective study

CJDSU, retrospective study  2

CJDSU, terms of reference

CJDSU, Third Annual Report  2

CJDSU, work of the Unit 1990-96  2

clinical criteria

clinical histories

clinical symptoms  2

clinical tests

CMO  2,  3,  4,  5,  6,  7,  8,  9

CMO's Committee on the Human Aspects of Spongiform Encephalopathies

codon 129 genotype  2,  3,  4,  5,  6

cognitive impairment

Collinge, Professor John  2

Committee on Safety of Medicines see CSM

Communicable Disease Surveillance Centre see CDSC

computerised axial tomography see CT

Consultative Committee on Research into Spongiform Encephalopathies see Tyrrell Committee

Coroner's Society of England and Wales  2

coroners

Coroners (Practice & Procedure) Rules (Northern Ireland) 1963

Coroners Act (Northern Ireland) 1959

Coroners Act 1988  2

Coroners Rules 1984

Coroners' Society of England and Wales

cortical

cortical blindness

Cousens, Dr Simon  2

Creutzfeldt-Jakob Disease see CJD

CSM  2

CT scans

CVL

D

dairy farm workers  2,  3,  4

dairy farmers  2,  3,  4,  5

DCMO

death certificates  2,  3

death certification

dementias  2,  3

Department of Health see DH

Department of Health, Research Division

Deputy Chief Medical Officer see DCMO

Deputy CMO

DH  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12,  13,  14,  15,  16

DH, Health Aspects of the Environment and Food Division  2

DH, Research and Development Division

diagnosis  2,  3,  4

dietary factors  2,  3,  4,  5

disabled units

disinfection procedures, scrapie agent

district nurses

DNA analysis

DNA sequencing

dysaesthesiae

E

Eddy, Thomas  2,  3,  4

Edinburgh Western General Hospital

EEG  2

electroencephalograms  2,  3

Environmental Health Departments

EU Surveillance Group

European BIOMED 1 programme

European CJD surveillance

European farmers

European surveillance  2

F

familial

familial CJD  2,  3,  4,  5

farm workers

farmers  2,  3,  4,  5,  6,  7,  8,  9,  10

farming

Fatal Accidents and Sudden Deaths Inquiry (Scotland) Act 1976

fatal accidents inquiries, Scotland

ferrets

food questionnaires  2

Freeman, Roger (Lord)

frontotemporal dementias  2

funeral directors

G

general practitioner see GP

genetic analysis for diagnosis

genetic mutations  2,  3

genetic studies

geographical distribution

germ lines

Gerstmann-Sträussler Syndrome see GSS

glial cell proliferation

goat meat

Gore, Dr Sheila  2

GP care  2

GP diagnosis

growth hormone see hGH (human growth hormone)

GSS  2,  3

H

health risks

healthcare professionals

healthcare professionals, perceived health risks

herdsmen

hGH  2

hGH recipients

hGH-derived CJD

Hofman, Professor Albert  2

homozygotes  2,  3,  4,  5

hospices

hospital admission for diagnosis  2

Hospital records

hospitals

hospitals, communication

hospitals, information provision

Human BSE Foundation  2

human growth hormone see hGH

human growth hormone-derived CJD see hGH-derived CJD

I

iatrogenic CJD  2,  3,  4

incubation period

inherited CJD see familial CJD

inquests  2

inquests, Northern Ireland

Ironside, Dr James  2,  3,  4,  5

Irwin Mitchell (solicitors)

Irwin, Stephen QC  2

J

K

Kimberlin, Dr Richard

kuru  2,  3

L

laboratory workers

Lacey, Professor Richard

Leckey, John

Levy, Dr Katherine  2

Lister, Charles  2,  3,  4

lumbar puncture

lymphoid tissue

M

MAFF  2,  3,  4,  5,  6,  7

magnetic resonance imaging see MRI

Matthews, Professor Bryan  2,  3,  4,  5,  6,  7

McGovern, Dr Michael

meat and bone meal

mechanically recovered meat  2

medical registers

Medical Research Council see MRC

medicinal products of bovine origin.

Medicines Inspectorate

methionine homozygotes  2,  3,  4

Metters, Dr Jeremy

milk  2,  3

Milner, Dr Robert

Ministry of Agriculture, Fisheries and Food see MAFF

MLC briefing paper

mortuary staff

motor neurone disease

MRC 10, 14

MRC Allen Committee  2

MRC Coordinating Committee for Research on Spongiform Encephalopathies in Man (The Murray Committee)  2

MRC Working Group on CJD  2

MRC, Allen Committee  2

MRC, Allen committee, meetings

MRI

multiple sclerosis

Murray, Thomas

myoclonus  2

N

National Hospital of Neurology and Neurosurgery, London

neurological examination

neurological symptoms  2

neurologist referral

neurologists

neuropathology

neuropathology surveillance

neurosurgical cross-contamination  2

NHS

non-invasive tests

Northern Ireland  2

Northern Ireland, inquests

Northern Ireland, registration of deaths

O

occupational exposure  2,  3,  4,  5,  6

occupational therapists

Office of Population Censuses and Surveys see OPCS

OPCS  2,  3,  4,  5

Oxford University, Department of Neurology

P

paediatric surveillance

Palmer, Dr Mark

Palmer, Professor Stephen

Parliamentary Food and Health Forum

Pattison, Professor Sir John  2

phenotypes  2,  3,  4,  5,  6

PHLS  2,  3,  4,  5,  6,  7,  8,  9,  10

PHLS, Accountability Review  2

PHLS, and CJD surveillance

PHLS, dissemination of information

physiotherapists

Pickles, Dr Hilary  2,  3,  4,  5,  6,  7,  8

pig farmers

pithing

Pituitary Hormone Laboratory, Cambridge

plaques  2,  3,  4,  5,  6,  7,  8,  9,  10,  11

post-mortem examination

poultry batteries

poultry farmers

primates

The Prion Disease Group, St Mary's Hospital, London

prion disease  2,  3

prion protein  2,  3,  4,  5,  6

prion protein gene

prion protein gene mutation  2,  3,  4

prion protein genotype

prion protein, diagnostic techniques

prions, biochemical detection

processed meat

psychiatric symptoms  2

psychiatrist referral

psychiatrists

Public Health Laboratory Service see PHLS

Q

questionnaires  2,  3,  4,  5,  6

R

reflexes

Registration of Births and Deaths Regulations 1987  2

Registration of Births and Deaths Regulations 1987, Regulation 41

registration of deaths, Northern Ireland

registration of deaths, Scotland

Reye's syndrome

Roberts, Dr Gareth  2

Rossor, Professor Martin  2

Rubery, Dr

S

Salmon, Dr Roland

Scotland  2

Scotland, fatal accident inquiries

Scotland, registration of deaths

Scottish Office

Scottish Office, Home and Health Department

scrapie  2,  3,  4,  5,  6,  7

scrapie agent  2

SEAC  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12,  13,  14,  15,  16,  17,  18,  19,  20,  21

SEAC, Epidemiology Subcommittee

Shaw, Professor David  2

sheep meat

Skinner, Dr Roger

Skinner, Mike

slaughtermen  2,  3,  4

Slovakia

slow viruses

Smith, Dr (Sir) Joseph  2,  3,  4,  5

Smith, Professor Peter  2,  3,  4,  5,  6

social services  2

somatic cells

Southwood Working Party on Bovine Spongiform Encephalopathy  2,  3,  4

spinal cord  2

Spongiform Encephalopathy Advisory Committee see SEAC

sporadic CJD  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12

SSPE see subacute sclerosing panencephalitis

strain typing  2,  3

subacute sclerosing panencephalitis  2

susceptibility factors

symptoms  2

T

Taylor, Kevin  2

teenagers  2,  3,  4,  5,  6

tests

tests, non-invasive

thalamic gliosis

thalamus

TME

tonsil biopsy

tonsils

transmissible mink encephalopathy see TME

transmission studies

TSE

Tyrrell Committee  2,  3,  4,  5,  6

Tyrrell Consultative Committee on Research into Spongiform Encephalopathies see Tyrrell Committee

Tyrrell, Dr David  2,  3,  4

U

undertakers

United States Department of Agriculture see USDA

USDA  2

V

vaccines  2,  3

valine homozygotes  2,  3

variant CJD see vCJD

vCJD  2,  3,  4,  5,  6,  7,  8,  9

vCJD patients, aids and equipment  2

vCJD patients, burial/cremation issues

vCJD patients, care at home

vCJD patients, families

vCJD patients, post-mortem isues

vCJD patients, treatment and care  2

vCJD, and BSE  2,  3,  4,  5,  6

vCJD, cases

vCJD, clinical symptoms

vCJD, clustering

vCJD, emergence 1989-95  2

vCJD, identification  2,  3

vCJD, incidence  2

vCJD, patients, financial costs

veal

venison

veterinarians  2,  3

W

Walford, Dr Diana  2,  3,  4

Walton, Professor (Lord)  2,  3

Western General Hospital, Edinburgh  2

white pudding

Wight, Dr Ailsa  2,  3,  4

Wilesmith, Mr

Will, Dr Robert  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12,  13,  14,  15,  16,  17,  18

Will, Professor Robert  2

X

Y

young patients  2,  3,  4,  5,  6,  7,  8,  9,  10,  11

young patients, summary tables  2

young people  2,  3,  4

Z

Ziedler, Dr Martin