Volume 7: Medicines and Cosmetics
Index

C

Cabinet, concerns regarding vaccines

Cabinet, consideration of Southwood Report

calcium gluconate

calf serum

calf serum, research proposal for

calves  2

calves foot jelly

calves, as tissue source  2,  3,  4,  5

calves, brain

Cameron, Mr  2

Campbell, Professor  2,  3

carcasses

carcasses, routes of use

carcasses, uses of

cardiac patches

carnivores, introduction of BSE into

casein

cat, development of spongiform encephalopathy in  2

catalase

catgut

catgut, alternative sourcing

catgut, bovine-derived  2,  3,  4,  5,  6,  7,  8,  9,  10,  11

catgut, from sheep intestine

catgut, proximity of source material to lymphoid tissue

catgut, Question and Answer briefing

catgut, use in neurosurgery  2,  3

cattle  2

cattle feedingstuffs

cattle, infection from scrapie-infected sheep

cauls

Cawthorne, Dr

CDSM see Committee on Dental and Surgical Materials

CEC see Commission of the European Communities

cell cultures  2,  3,  4,  5,  6

cell lines  2,  3

cellular triple vaccine

Central Veterinary Laboratory (CVL)  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12,  13,  14,  15,  16,  17,  18,  19,  20,  21,  22

cerebrosides  2

cerebrospinal fluid

certification of clinically disease-free animals

Channel Islands 154, 250, 251, 257

Channel Islands, application of guidelines to

cheek meat

Chemical Division, Porton Down

Chemical Hazards Section (CHS)  2

Chemical Safety Section, DTI

Chief Medical Officer (CMO)  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12

Chief Medical Officer (CMO), draft submission to Secretary of State

Chief Medical Officer (CMO), reaction to BSE

Chief Pharmaceutical Officer

Chief Pharmacist

Chief Scientists Group (CSG)  2,  3

Chief Scientists Group, MAFF

Chief Veterinary Officer (CVO)  2,  3,  4,  5,  6

CHS see Chemical Hazards Section

Civil Service

Clarke, Mr Kenneth  2,  3,  4,  5,  6,  7

clean beef cattle  2,  3

clean beef herds

Clinical Research Centre  2

Clinical Trial Certificate (CTC)  2,  3,  4,  5

Clinical Trial Exemption (CTX)

closed herds  2,  3,  4

CMO see Chief Medical Officer

coconut oil

Coleman, Mr

COLIPA  2,  3,  4,  5,  6

collagen  2,  3,  4,  5,  6,  7

collagen implants  2,  3,  4,  5,  6

collection techniques for tissue samples  2,  3

Collee, Professor  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12,  13,  14,  15,  16,  17,  18,  19,  20,  21,  22,  23,  24,  25,  26,  27,  28,  29

Collee, Professor, opinion regarding gelatine

Collee, Professor, statement of

colostrum

Commercial in Confidence

Commission Decision 96/239/EC

Commission Directive 97/1/EC

Commission of the European Communities (CEC)

Committee for Proprietary Medicinal Products (CPMP)  2,  3,  4,  5,  6

Committee for Proprietary Medicinal Products (CPMP), classification of tissues

Committee for Proprietary Medicinal Products (CPMP), guidelines  2,  3

Committee for Veterinary Medicinal Products (CVMP)  2,  3

Committee for Veterinary Medicinal Products (CVMP), guidelines

Committee on Dental and Surgical Materials (CDSM)  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12,  13,  14,  15,  16,  17,  18

Committee on Dental and Surgical Materials (CDSM), BSEWG meeting report

Committee on Dental and Surgical Materials (CDSM), consideration of BSE Working Group recommendations  2

Committee on Dental and Surgical Materials (CDSM), views on catgut

Committee on Review of Medicines (CRM)  2,  3,  4,  5,  6,  7,  8,  9

Committee on Review of Medicines (CRM), consideration of products of concern

Committee on Review of Medicines (CRM), meeting

Committee on Safety of Medicines (CSM)  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12,  13,  14,  15,  16,  17,  18,  19,  20,  21

Committee on Safety of Medicines (CSM), Biologicals Sub-Committee (CSM/BSC) 19, 41, 54, 55, 56, 62, 63, 65, 67, 70, 72, 73, 76, 79, 96, 136, 189

Committee on Safety of Medicines (CSM), BSEWG meeting report

Committee on Safety of Medicines (CSM), consideration of BSE Working Group recommendations

Committee on Safety of Medicines (CSM), consideration of guidelines  2

Committee on Safety of Medicines (CSM), endorsement of BSE Working Group recommendations  2

Committee on Safety of Medicines (CSM), establishment of working party

Committee on Safety of Medicines (CSM), joint CSM/VPC guidelines  2

Committee on Safety of Medicines (CSM), policy on human medicinal products

Committee on Safety of Medicines (CSM), position statement  2

Committee on Safety of Medicines (CSM), Southwood letter

Committee on Safety of Medicines (CSM), Working Party on BSE

Committee on Safety of Medicines, joint CSM/VPC guidelines

Committee on the Adaptation to Technical Progress

Committee on the Review of Medicines (CRM)  2

committees, role of

Communicable Diseases Branch

compliance with guidelines  2

computing and information technology

condemned meat

Consultative Committee on Research

Consumer Protection Act 1987  2,  3,  4,  5

Consumer Safety Division

Consumer Safety Unit (CSU)  2,  3

contact lens products

contact lenses

contamination  2,  3,  4,  5,  6

Coopers-Pitman Moore

coordinated approach, lack of

corticosteroids  2

Cosmetic Products (Safety) Regulations 1984

Cosmetic Products (Safety) Regulations 1989

Cosmetic Products Safety Regulations

Cosmetic Products Working Party

cosmetics  2,  3,  4,  5,  6,  7,  8

Cosmetics Directive  2,  3,  4,  5,  6,  7,  8,  9,  10,  11

cosmetics industry

Cosmetics Products (Safety) Regulations 1996

cosmetics, and BSE  2

cosmetics, definition of

cosmetics, DH role in safety

cosmetics, enforcement of safety regulations

cosmetics, handling by DTI

cosmetics, questionnaire  2

cosmetics, regulation of  2

Cosmetics, Toiletries and Perfumery Association (CTPA)  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12,  13,  14,  15,  16,  17

Cosmetics, Toiletries and Perfumery Association (CTPA), contact with DH

Cosmetics, Toiletries and Perfumery Association (CTPA), guidelines

Cosmetics, Toiletries and Perfumery Association (CTPA), response to questionnaire

Council Directive 65/65/EEC

Council Regulation 2309/93

covering letters to guidelines  2,  3,  4

covering letters to guidelines, wording of

cowhands

CPMP see Committee for Proprietary Medicinal Products

Crawford, Mr

creams

Creutzfeldt-Jakob disease (CJD)  2,  3,  4,  5

Creutzfeldt-Jakob disease (CJD), causative agents

Creutzfeldt-Jakob disease (CJD), iatrogenic

Creutzfeldt-Jakob disease (CJD), new variant  2

Creutzfeldt-Jakob disease (CJD), risk of contracting

Creutzfeldt-Jakob disease (CJD), transmission in pituitary hormone extracts

Creutzfeldt-Jakob disease (CJD), transmission via human growth hormone

Creutzfeldt-Jakob disease (CJD), vertical transmission

CRM see Committee on Review of Medicines

cross-contamination  2,  3

cross-membership of key advisory committees

Cruickshank, Mr Alistair  2,  3,  4,  5,  6,  7,  8,  9,  10,  11

CSG see Chief Scientists Group

CSM see Committee on Safety of Medicines

CSM/BSC see Committee on Safety of Medicines, Biologicals Sub-Committee

CSU see Consumer Safety Unit

CTC see Clinical Trial Certificate

CTPA see Cosmetics, Toiletries and Perfumery Association

CTX see Clinical Trial Exemption

culture media  2,  3,  4

Cunliffe Report  2,  3

Cunliffe, Mr P W  2,  3,  4,  5,  6,  7

Currie, Mrs Edwina  2

CVL see Central Veterinary Laboratory

CVMP see Committee for Veterinary Medicinal Products

CVO see Chief Veterinary Officer

Cyanamid

D

Dastgir, Dr  2

Dayan, Professor Anthony  2

DCMO see Deputy Chief Medical Officer

deer  2,  3

Denmark

dental products

Department of Education and Science (DES)

Department of Health (DH)  2,  3,  4,  5,  6,  7,  8,  9,  10,  11

Department of Health (DH), awareness of BSE

Department of Health (DH), contact with CTPA

Department of Health (DH), DTI seeks advice on cosmetics

Department of Health (DH), inadequacy of record keeping

Department of Health (DH), issue of joint CSM/VPC guidelines

Department of Health (DH), issue of joint guidelines

Department of Health (DH), lack of communication with MAFF  2

Department of Health (DH), perceptions of

Department of Health (DH), Research Management Division  2

Department of Health (DH), response to audit proposal

Department of Health (DH), responsibility for human medicines licensing

Department of Health (DH), responsibility for safety of human and veterinary medication

Department of Health (DH), role in cosmetic safety

Department of Health (DH), updated advice for CTPA

Department of Health and Social Security (DHSS)  2

Department of Trade and Industry (DTI)  2,  3,  4,  5,  6,  7

Department of Trade and Industry (DTI), action taken by  2

Department of Trade and Industry (DTI), Chemical Safety Section

Department of Trade and Industry (DTI), handling of cosmetics

Department of Trade and Industry (DTI), information given to  2

Department of Trade and Industry (DTI), seeking DH advice on cosmetics

Deputy Chief Medical Officer (DCMO)  2,  3,  4,  5,  6

Deputy Chief Pharmacist

DES see Department of Education and Science

Dewhurst, Dr

DH see Department of Health

DHSS see Department of Health and Social Security

diaphragm  2

Diggle, Dr

diphtheria vaccine  2

diphtheria, tetanus, pertussis vaccine  2,  3,  4,  5

disease-free herds  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12,  13,  14,  15,  16,  17,  18

disease-free herds, definition of  2

Dixon, Mr

Dorrell, Mr Stephen

Downer Syndrome

dressings

DTI see Department of Trade and Industry

Duncan, Miss Marilyn  2,  3,  4,  5,  6,  7,  8,  9

Duphar Laboratories

dura mater  2,  3

dura mater, human  2

dural implants  2

E

ears

EC Agriculture Commissioner

EC Directive 81/851/EEC

EC see European Community

EC Working Party on Cosmetics (ECWPC)  2,  3,  4,  5,  6,  7,  8

ECWPC see EC Working Party on Cosmetics

Eddy, Mr Thomas  2,  3,  4,  5,  6,  7,  8

edible fat

Eire see Republic of Ireland

Eisen, Dr

elastin  2

embryo transfer  2

embryos

EMEA see European Medicines Evaluation Agency

Emergency Vaccines

encephalopathic syndrome

England

epidemiological flowchart  2

esters

Ethicon  2,  3,  4

Ethicon, safety measures proposed by

EU see European Union

European Community (EC)  2

European Community (EC), licensing procedures

European guidelines  2,  3,  4,  5

European guidelines, audit of compliance

European guidelines, finalisation of

European guidelines, further consideration

European guidelines, human medicines

European guidelines, revision of

European guidelines, veterinary medicines

European Medicines Evaluation Agency (EMEA)  2

European Union (EU)  2

European Union (EU), increased involvement with BSE crisis

European Union (EU), licensing arrangements

European working party on human medicines

Evans Medical  2

Evans Medical, response to questionnaire

Evans, Dr N J B  2

Evans--Cunliffe Report

Evans-Cunliffe Report  2,  3

excepted premises  2,  3,  4

excepted premises, definition of

excipients  2,  3,  4,  5

excretions, isolation of scrapie from

Executive Agencies  2,  3,  4,  5,  6,  7

Executive Support Division, MCA

Executive Support unit  2,  3

exemptions from SBO ban  2,  3,  4

exemptions from SBO ban, second thoughts on

existing stocks  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12,  13,  14

existing stocks, Ministers' involvement in decision

existing stocks, question of freedom from BSE

exotica  2,  3

eyes  2,  3

eyes, infectivity of

eyes, topical preparations  2,  3,  4,  5

F

faeces  2,  3

Falklands  2

farm hands, CJD not observed in

fat

fatty acids

FCS see foetal calf serum

FDA see Food and Drugs Administration

feed additives team, VMD

fellmongers

Ferguson, Dr

fibrin  2

Fielder, Dr Robin  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12,  13,  14,  15,  16,  17,  18,  19,  20,  21,  22

file tracking system

Finance Division, MCA

fish vaccines  2

foetal calf serum (FCS)  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12,  13,  14,  15,  16,  17,  18,  19,  20,  21,  22,  23,  24,  25,  26,  27

foetal calf serum (FCS), acceptability of use

foetal calf serum (FCS), alternative sourcing of

foetal calf serum (FCS), Australasian, as 'gold standard'

foetal calf serum (FCS), collection of

foetal calf serum (FCS), difficulty in ensuring freedom from contamination

foetal calf serum (FCS), in rubella vaccine

foetal calf serum (FCS), in vaccines

foetal calf serum (FCS), preparation of  2,  3,  4

foetal calf serum (FCS), promptness of research studies

foetal calf serum (FCS), suppliers of

foetal fluids  2,  3

foetal lambs, scrapie infection in

follicle stimulating hormone

Food and Drugs Administration (FDA)

Food Hygiene and Safety Branch

Food Safety Act 1990

Food Safety Branch

Food Science Division

Foot and Mouth Disease (Sera and Glandular Products) Order

Foster, Dr

fourth International Scientific Congress in Fur Animal Production

France  2,  3,  4,  5,  6,  7

France, bovine material from

France, BSE in  2,  3

France, Higher Council of Public Hygiene  2

France, request for update on UK BSE outbreak

France, suture products sourced in

Fraser, Dr

Freeman, Mr Roger  2

French Ministry of Health

Fry, Mr

funding of research

G

gall  2

gallstones

gangliosides  2

Garland, Dr A  2

gelatine  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12,  13,  14

gelatine, capsules

gelatine, coating

gelatine, consideration by CSM

gelatine, in cosmetics

gelatine, in foods

gelatine, in pharmaceuticals

gelatine, production of

gelatine, safety of

General Product Safety Regulations 1994

genital organs

genome

German delegation to BWP  2

German Federal Health Office (BGA)

German guidelines  2,  3,  4

German numerical factor system, unacceptability of

Germany  2,  3

Glaxo Wellcome  2

glucagon  2

glycerol

glycerol beef broth  2

goats  2,  3,  4,  5,  6

gold files  2

gonadotrophin

Gott, Dr  2,  3

Gray, Mr Alastair  2

Green, Miss

guidelines  2

guidelines, as 'purely precautionary measure'

guidelines, as gold standard  2,  3

guidelines, compliance with  2

guidelines, conclusions on follow-up  2

guidelines, consideration by CSM

guidelines, covering letters  2,  3,  4,  5

guidelines, European  2,  3

guidelines, joint CSM/VPC  2,  3,  4

guidelines, medical devices  2

guidelines, NOAH's concerns

guidelines, non-binding, appropriateness of

guidelines, preparation and issue  2

guidelines, review of

guidelines, scope of

guinea-pig

Gummer, Mr John  2,  3,  4,  5,  6,  7,  8,  9,  10,  11,  12,  13

gut room