Volume 16: Reference Material
Table of Contents

1. BSE chronology

2. Summary of the spread of BSE, 1985-88

3. Statistics
   Introduction
   Definition of key terms
   Incidence by clinical onset
   Incidence by notification
   Incidence by herd, type of herd and breed
   Suspect and confirmed cases
   Confirmed cases: contemporaneous and revised
   Cases Born After the feed Ban (BABs)
   BSE cases by year of birth
   BSE statistics outside the UK
   Other spongiform encephalopathies
   Scrapie statistics
   Creutzfeldt-Jakob Disease

4. Uses made of the cattle carcass
   Rendering
   Gelatine
   Circularity in the use of the cattle carcass
   Figure 4.1: The cattle carcass: routes of use in the late 1980s

5. Illustrations
   Figure 5.1: Beef: position of cuts
   Figure 5.2: Diagrammatic sketch of the main anatomical parts of the digestive system of the cow
   Figure 5.3: Specified Bovine Offal as specified by the SBO Order 1995
   Figure 5.4: Position of the thymus gland
   Figure 5.5: Schema of the abdominal lymph nodes of the ox
   Figure 5.6: Bovine sagittal section through the brain, showing position of the obex section
   Figure 5.7: Spinal cord: cross-section with nerve roots on left side and examples of tracts on right side
   Figure 5.8: Section through the human skull and brain
   Figure 5.9: Coronal section through the human brain
   Figure 5.10: Sagittal section through the human brain
   Figure 5.11: BSE: section from bovine brain showing extensive spongiform change
   Figure 5.12: BSE: neuronal axon showing PrP^Sc accumulation on neurite membrane
   Figure 5.13: Normal human brain structure: section of cerebral cortex showing large darkly stained neurones (centre) in surrounding grey matter (haematoxylin and eosin stain)
   Figure 5.14: Sporadic CJD: section of cerebral cortex showing reduction in number of neurones and vacuolation in surrounding grey matter
   Figure 5.15: Variant CJD: section of cerebral cortex showing large florid plaque (centre) surrounded by spongiform change (vacuolations)
   Figure 5.16: Variant CJD: section of cerebral cortex stained to show aggregates of PrP^Sc within plaques and more finely distributed throughout the grey matter (PrP stains brown)
   Figure 5.17: A slaughterhouse worker, late 1980s

6. Ministerial charts
   Figure 6.1: MAFF Ministers
   Figure 6.2: Health Ministers
   Figure 6.3: Welsh Office Ministers
   Figure 6.4: Scottish Office Ministers
   Figure 6.5: Northern Ireland Office Ministers

7. The organisation of MAFF and DH, 1986-96
   Introduction: the purpose of this commentary
   Ministry of Agriculture, Fisheries and Food (MAFF)
   How MAFF changed
   Chart A1: MAFF Structure, 1986 to October 1989
   Chart A2: Animal Health Group, 1986 to October 1990
   Chart A3: Emergencies, Food Quality & Pest Control, 1986 to October 1989
   Chart A4: ADAS, 1986-89
   Chart A5: Chief Scientists' Groups, including Food Science Group, January 1988 to October 1989
   Chart A6: State Veterinary Service (SVS), 1986 to November 1990
   Chart A7: Meat Hygiene (Veterinary Section) 1986 to March 1996
   Chart A8: Central Veterinary Laboratory, 1986 to April 1990 (became a MAFF Executive Agency in April 1990)
   The establishment of the Food Safety Directorate, November 1989
   The creation of the Animal Health and Veterinary Group, 1990
   Chart B1: MAFF, November 1989 to October 1994
   Chart B2: Animal Health & Veterinary Group, November 1989 to October 1994
   Chart B3: Veterinary Field and Investigation Service, November 1989 to October 1994 (merged with AHG in 1990)
   Chart B4: Food Safety Group, November 1989 to October 1994
   Chart B5: Food Science Group, November 1989 to October 1994
   Chart B6: Central Veterinary Laboratory (1985-96), TSE Staff
   The demerger of the Animal Health and Veterinary Group (AHVG)
   Chart C1:MAFF, November 1994 to March 1996
   Chart C2:Animal Health Group, November 1994 to March 1996
   Chart C3:Meat Hygiene Division, November 1989 to March 1996
   Chart C4:State Veterinary Service, November 1994 to March 1996
   The Department of Health (DH)
   Organisational changes, 1986-96
   DH organisation charts
   Chart 1:DHSS, 1986-88
   Chart 1A: Services Development Group, 1986-87
   Chart 1B: Medical Divisions (Health and Personal Services), 1986-88
   Chart 2: Department of Health, 1988-91
   Chart 2A: Health and Personal Social Services Group, 1988-90
   Chart 2B: Environmental Health and Food Safety Division, 1990-91
   Chart 2C: Medical Divisions (Health and Personal Services), 1988-91
   Chart 2D:Medicines Division April 1988 to 1991
   Chart 2E: Medicines Control Agency, 1990-95
   Chart 3:Department of Health 1992-94
   Chart 3A: Health and Personal Social Services Group, 1992
   Chart 3B: Health and Social Services Group, 1993-94
   Chart 4:Department of Health, April 1995 to 1996
   Chart 4A:Health Aspects of Environment and Food Division, April 1995 to 1996

Glossary
   Dictionary references

Who's who
   Explanation of the S and T codes